IgG4-Related Disease (IgG4RD)
What is IgG4-Related Disease (IgG4RD)?
IgG4-Related Disease (IgG4RD) is a chronic autoimmune condition in which the immune system mistakenly causes inflammation, swelling, and fibrosis (scarring) in one or more organs. It can affect the pancreas, salivary and lacrimal glands, lymph nodes, kidneys, lungs, and sometimes the heart or nervous system. The condition often presents with painless swelling, organ enlargement, or mass-like lesions that may be confused with infections or cancer. Early diagnosis is essential to prevent long-term organ damage.
How IgG4RD is Treated
Treatment focuses on controlling inflammation and preventing relapse. Management generally includes:
- Corticosteroids to reduce active inflammation
- Immunosuppressive medications to maintain remission
- Biologic therapies for severe or recurrent disease
- Organ-specific management, especially for the pancreas, kidneys, or lungs
- Regular monitoring, including imaging and IgG4 blood levels
With appropriate treatment, most individuals respond well and achieve stable control of the disease.
If you are experiencing unexplained swelling, organ-related symptoms, or have been advised to evaluate for IgG4RD, you may book a consultation with Dr. Harsh Jain for IgG4-Related Disease Treatment in Mumbai. Please visit our website or reach out through the contact numbers provided.